In fall 2016, I am opening my lab at University College London funded by a MRC Career Development Award ("The computational psychiatry of major depressive disorder"). My lab will be located on Russell Square at the new Max Planck Centre for Computational Psychiatry and Ageing Research.
Depression is the leading cause of disability worldwide, affecting more than 300 million people. Unfortunately, current antidepressant treatments do not help many of those who suffer from the disorder. It is now widely accepted that depression can result from a variety of different sources, much like a cough can have many different underlying causes. There is currently no reliable way for a psychiatrist to know which treatment is likely to be the most effective for helping a particular depressed individual. If we can identify the causes, we can treat depression more effectively.
Our research lies at the intersection of decision and affective neuroscience and combines computational modeling with neuroimaging, pharmacology, and smartphone-based data collection. By incorporating subjective ratings into a variety of decision tasks, we will examine the neural circuits that determine mood and explain its relation to behaviour in healthy and depressed individuals.